一、建立并完善新药临床前药理学研究体系
To establish and perfect preclinical pharmacology study system on new drugs
1、建立并完善计划生育和生殖健康动物模型
关键词:避孕、壮阳和抗早泄
To establish and perfect animal models of planned parenthood and reproductive health
Key words: Contraception, Aphrodisiacs and Anti-premature Ejaculation
2、建立并完善前列腺炎疾病模型的建立和完善
关键词:增生、肿瘤和前列腺炎
To establish and perfect prostatic disease models
Key Words: Hyperplasia, Tumour and Prostatitis
3、建立并完善子宫内膜异位大鼠和家兔模型
关键词:大鼠、家兔和内异症
To establish and perfect endometriosis rats and rabbits models
Key Words: Rat, Rabbit and Endometriosis
二、建立并完善新药临床前安全性评价系统
To establish and perfect new drugs preclinical safety evaluation system
1、规范和完善新药临床前安全性评价试验操作
To establish and perfect preclinical safety evaluational operation on new drugs
关键词
Key Words:
(1)单次给药毒性试验(包括啮齿类和非啮齿类)
Single Dose Toxicological Study (including rodents and non-rodentia);
(2)多次给药毒性试验(包括啮齿类和非啮齿类)
Mutiple Dose Toxicological Study (including rodents and non-rodentia);
(3)局部毒性试验
Local Toxicological Study;
(4)安全性药理试验
Safety Pharmacology Study;
(5)生殖毒性试验
ReproductiveToxicological Study;
(6)遗传毒性试验
Genetic Toxicological Study;
(7)免疫原性试验
Immunogenic Toxicological Study ;
(8)毒代动力学试验
Toxicokinetics Study;
(9)致癌试验。
Carcinogenesis Study
2、遵循OECD组织倡导的安全性操作规范规定
To follow the safety operation procedure (SOP) proposed by OECD
3、寻找国际跨国制药企业和/或CRO 公司合作
To establish the cooperation with multinational pharmaceutical manufacture enterprise and/or CRO companies.
三、利用上述体系和系统进行生殖健康研究
Research on Reproductive Health With Study System Above
1、为全球制药企业服务,开展药理毒理学研究
To develope pharmacology and toxicology research, to serve the global pharmaceutical manufacture enterprise.
2、为整个人类健康服务,开发生殖健康的产品
To develope reproduction health products, to servese the whole human beings health.
关键词:
key words:
药物安全性评价
Drugs Safty Evaluation
前列腺炎炎疾病防治
Prevention and Cure of Prostate Diseases
防治艾滋病药物
Drugs to Prevent and Control AIDS
抗子宫内膜异位症
Anti-endometriosis Uterina